DuckStation supports automatic detection disc regions, and if you set the console region to auto-detect as well, this should never be a problem.
Some states do not allow the exclusion or limitation of incidental or consequential dam-ages, so the above limitation or exclusion may not apply to you.
I have the core fully updated according to Option #2 - Creating a game list Go to Settings > Game List Settings. No lag reduction: ssspsx, pc fps, cpu overclock, artificial multithreading. It focus on performance rather than accuracy and a Retroarch core exists, so it should work on the Pi. After that, you need to choose the file you need according to your operating system version.